Disorders of endocrine systems encompass some of the most common problems encountered by practicing physicians, result in substantial morbidity and mortality to patients, and represent a massive economic burden to our society. The Endocrine Sciences portion of the course encompasses a plan of study resulting in a thorough understanding of the principles of hormone action and hormonal systems, and the physiology of the major endocrine systems. Students learn the pathophysiologic mechanisms by which these systems may become deranged, and how these derangements present clinically in the form of classic endocrine disorders. Students learn the appropriate approach to patients with endocrine disorders, using diagnostic testing algorithms and pharmacologic agents based on a logical application of their knowledge of endocrine biochemistry, physiology and pathophysiology. Students are exposed to the essential anatomy, pathology, histopathology and radiology of normal and abnormal endocrine organs.