Fundamentals is the first course of the M1 year, which is comprised of four 4-week blocks (for a total of 16 weeks) through the entire fall semester. This integrated course provides entering CMSRU students with a shared solid understanding of the full spectrum of basic science concepts and disciplines, such as: genetics, molecular and cell biology, biochemistry and metabolism, histology and introductory pathology, embryology, pharmacology and toxicology, basic neurosciences, microbiology, immunology, and cancer biology. Fundamentals also introduces our students to the CMSRU approach to curriculum delivery, utilizing a diverse combination of traditional and “flipped” lectures, interactive “application” sessions and small-group learning activities (active learning groups, team-based learning, and “jigsaws”).